Quick Start

Create your first AI-generated genetic circuit in under five minutes.

1. Sign up

Go to nuclex.dev/sign-up and create an account. The free plan includes 10 AI credits per month.

2. Create a project

From the Dashboard, click New Project. Give it a name and optionally set a default organism (e.g., Escherichia coli).

3. Create a design

Open your project and click New Design. This opens the circuit editor with an empty canvas.

4. Generate with AI

Open the AI panel on the right side of the editor and type a natural-language prompt:

Design a biosensor that detects arsenic and produces GFP in E. coli

The AI pipeline will parse your intent, retrieve matching parts from the database, assemble a circuit, validate it, and render the result on the canvas. You will see progress through each stage in real time.

5. Review and refine

Inspect each part by clicking on it. The Part Inspector shows the part name, type, sequence, and characterization data. You can:

• Swap a part for an alternative from the parts browser
• Reorder parts by changing their sort order
• Chat with the AI to refine the design (“Replace the promoter with something stronger”)

6. Validate

Click Validate in the toolbar to run five biological checks: codon optimization, promoter-RBS compatibility, restriction site conflicts, metabolic burden, and terminator read-through. Fix any errors before exporting.

7. Export or order synthesis

Click Export to download your design as SBOL, GenBank, FASTA, or JSON. Or click Order Synthesis to get instant quotes from Twist and IDT.

8. Report outcomes

After testing your design in the lab, come back and click Report Outcome on the design card. Your feedback helps improve AI accuracy for everyone.